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A cash-pay medical marketplace with a bundled weight-loss subscription
Also searched as: Success by Sesame, Sesame Care
$59/mo
Brand + compounded
Cash-pay
August 30, 2026
Sesame is a direct-to-patient marketplace where clinicians publish their own cash prices and you book them without insurance in the middle. Success by Sesame is its packaged weight-loss subscription, layered on top of that marketplace.
The pricing is unusually legible for this category. Sesame publishes a subscription fee separately from medication cost, so you can see exactly what the clinical care costs versus what the drug costs. When it launched compounded semaglutide, Sesame explicitly marketed it "at cost" with no retail markup on the medication itself.
Sesame also runs a Costco partnership that gives Costco members discounted rates across the marketplace, including on the weight-loss program.
Sesame lists both FDA-approved brand-name GLP-1s and, historically, compounded semaglutide priced at cost. Availability of compounded products has narrowed industry-wide since the FDA shortage allowances ended — confirm what is currently offered before subscribing.
Book a video visit with a licensed clinician from the marketplace. You can see the clinician's price and availability before booking, which is rare in telehealth.
Adults meeting standard GLP-1 criteria (BMI 30+, or 27+ with a weight-related condition), subject to the clinician's judgment during the video visit.
Board-certified clinicians who set their own prices on the marketplace. The Success by Sesame subscription includes ongoing visits and follow-ups with your clinician rather than one-off consults.
Lab tests are included in the Success by Sesame program per Sesame's program description, which is a genuine differentiator — most flat-fee competitors exclude labs entirely.
Prescriptions can be sent to your pharmacy of choice for local pickup, or fulfilled by a partner pharmacy for the compounded program. Sesame does not run a captive pharmacy for brand-name drugs.
Depends on the fulfillment route. Local pharmacy pickup is available for brand-name prescriptions; partner-pharmacy shipping applies to compounded products.
Unlimited messaging with your clinician on the subscription, plus follow-up visits. Costco members get discounted rates across Sesame services.
$59 per month on an annual subscription, per Sesame's launch announcement. Medication is billed separately at that tier.
Billed separately from the subscription. Sesame has marketed compounded semaglutide at cost with no retail markup; brand-name medication is paid at the pharmacy.
Subscriptions can be cancelled through your Sesame account. Annual plans are prepaid, so cancelling mid-term does not necessarily refund the remaining months — confirm terms at signup.
No published blanket refund policy. Because the annual subscription is discounted for prepayment, treat it as a commitment rather than a month-to-month arrangement.
Sesame is built as a cash-pay marketplace and does not bill insurance for visits. There are no deductibles or out-of-network costs because insurance is not involved. You can still use insurance at the pharmacy for a brand-name prescription.
Sesame states membership prices may be payable through HSA/FSA. Visit fees and prescribed medication generally qualify as medical expenses; a Letter of Medical Necessity is typically needed for weight-loss drugs.
Pricing in this review reflects what Sesame and named third-party sources published as of August 30, 2026. Telehealth pricing changes frequently — confirm the current figure at checkout before you buy.
Cash-pay patients who want to see exactly what they are paying for, want lab work included, and are comfortable committing to an annual subscription for the lowest rate. Costco members get the best value here.
The annual-commitment discount structure means the advertised $59 rate is not what a month-to-month customer pays. If you want to test a program for one month, the effective cost is considerably higher. Reported pricing also varies across sources, so confirm the current figure at checkout.
Sesame's launch announcement lists the weight-loss subscription at $59 per month with an annual subscription, medication not included. Its program page also cites a starting price of $99 per month, and the original all-in compounded program launched at $249 per month including medication at cost. Confirm the current tier at checkout, since the figures have moved.
Yes. Sesame's program description lists lab tests among what is included, alongside video visits and follow-ups. That is a real differentiator — most flat-fee GLP-1 platforms exclude labs.
Costco members get exclusive pricing across Sesame, including $29 virtual care visits, $72 checkups and 10% off other services, which extends to the Success by Sesame program. You still need a Costco membership to access those rates.
No. Sesame is a cash-pay marketplace, so there are no deductibles, network restrictions or out-of-network costs on visits. You can still run a brand-name prescription through your insurance at the pharmacy.
Sesame lists brand-name GLP-1s including Wegovy in both pen and pill form, Ozempic, Zepbound, Mounjaro and Rybelsus. It has also offered compounded semaglutide priced at cost, though compounded availability has narrowed across the industry.
Sesame is an established telehealth marketplace connecting patients with licensed, board-certified clinicians who publish their own cash prices. It has been covered by Fierce Healthcare and has a national retail partnership with Costco.
Every pricing and policy claim on this page traces back to one of these sources, checked on August 30, 2026.
Subscription fee only; medication billed separately
Sesame's published starting figure for the weight-loss program
Historic launch price including clinical oversight and medication at cost
Costco members also get $72 checkups and 10% off other services
Verified August 30, 2026. Prices change often — confirm before purchase.
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This review is for informational purposes only and is not medical advice, a diagnosis, or a treatment recommendation. GLP-1 medications are prescription drugs with serious potential side effects and are not appropriate for everyone. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. Compounded medications are not FDA-approved. The FDA does not evaluate compounded products for safety, effectiveness, or quality. Individual results vary. This page contains affiliate links, and we may earn compensation if you use them.
Date reviewed: August 30, 2026