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28 telehealth programs compared on the numbers they actually publish — not the numbers they advertise.
Comparing GLP-1 providers is genuinely hard, and it is hard on purpose. Almost every platform advertises a low headline figure that turns out to be an introductory month, an annual-prepayment rate, a starting dose, or a membership fee that excludes the medication entirely. Two programs advertising "$99" can differ by $250 a month in what you actually pay.
This page strips that away. Every figure below comes from the provider's own published pages or from a named third-party source, and we separate the membership fee from the medication cost so you can see the real total. Where a provider does not publish a price, we say so rather than guessing.
One structural change shapes the whole market in 2026: the FDA resolved the semaglutide and tirzepatide shortages and ended the enforcement discretion that allowed mass compounding, and has proposed excluding both molecules from the 503B bulks list. At the same time, manufacturer-direct pricing collapsed — Foundayo now starts at $149 a month and Zepbound at $299. The gap that made compounding compelling has narrowed dramatically.
A "starting price" is the lowest published figure, which usually applies to an introductory month, an annual plan, or the lowest dose. Your real cost is the membership fee plus the medication cost at your maintenance dose. Add both columns together before comparing anything.
Sorted in the order reviewed. "Insurance" means the provider bills insurance for care or medication — compounded-only providers never can, because compounded drugs are not FDA-approved.
| Provider | Starting price | Medication type | Insurance | Membership fee |
|---|---|---|---|---|
| PlushCare | $19.99/mo membership | Brand-name | Yes | $19.99/mo or $149/yr |
| Sesame | $59/mo | Both | No | $59/mo on annual plan |
| LillyDirect | $149/mo | Brand-name | No | None |
| NovoCare Pharmacy | $149/mo | Brand-name | No | None |
| Amazon One Medical | $29/visit | Brand-name | Yes | None (pay per visit) |
| GoodRx for Weight Loss | $39/mo | Brand-name | No | $39/mo intro, $119 standard |
| Walgreens Virtual Healthcare | $49/visit | Brand-name | No | None (pay per visit) |
| Curex | $149/mo | Compounded | No | None |
| TrimRx | $199/mo | Compounded | No | None (bundled) |
| LumiMeds | $89/mo | Compounded | No | None (bundled) |
| Lemonaid Health | $49/mo membership | Both | No | $49/mo |
| Ivím Health | $74.99/mo membership | Compounded | No | $74.99/mo |
| Willow | $299/mo | Compounded | No | None (bundled) |
| MEDVi | $149 first month | Both | No | $99/mo on brand track |
| Fridays | $117/mo | Compounded | No | None (bundled) |
| Call-On-Doc | $39 one-time visit | Both | No | Optional $45/quarter |
| Nurx | $60 first month | Both | Yes | $79/mo provider fee |
| Klarity Health | $50/visit | Brand-name | Yes | None (pay per visit) |
| Good Life Meds | $174/mo | Compounded | No | None |
| Teladoc Health | $0 for eligible members | Brand-name | Yes | None (employer-paid) |
| Walmart Weight Management Care | $29/mo | Brand-name | Yes | Varies by care partner |
| Trimi | $99/mo | Compounded | No | None |
| Cora Health | $99/mo | Compounded | No | None (bundled) |
| Belle Health | $119/mo | Compounded | No | None (bundled) |
| Zealthy | $39 first month | Both | Yes | $135/mo ($39 intro) |
| Heally | $149/mo | Brand-name | No | None mandatory |
| Push Health | From $30/visit | Both | No | None (per-visit) |
| Raeliva | $139/mo | Compounded | No | None (bundled) |
Pricing verified from provider-published pages and named third-party sources. Telehealth pricing changes frequently — confirm at checkout.
These are the prices to benchmark everything else against. Both are FDA-approved brand-name medication bought straight from the manufacturer, with no compounding question and no platform markup.
| Medication | Channel | Self-pay price | Notes |
|---|---|---|---|
| Foundayo (orforglipron) | LillyDirect | From $149/mo | Oral tablet, FDA-approved April 1, 2026. $199 for 2.5 mg, $299 for higher doses |
| Zepbound (tirzepatide) | LillyDirect | $299-$449/mo | $299 for 2.5 mg, $399 for 5 mg, $449 higher. List price is $499-$1,086 per fill |
| Wegovy tablets | NovoCare Pharmacy | $149-$299/mo | $149 for 1.5 mg and 4 mg; 4 mg rises to $199 after August 31, 2026 |
| Wegovy injection | NovoCare Pharmacy | From $399/mo | Launched at a flat $499/mo in March 2025, now dose-tiered |
| Zepbound (retail pickup) | Walmart via LillyDirect | From $349/mo | Retail pick-up option launched October 2025 |
Neither manufacturer channel provides a prescriber. You need your own doctor, or a telehealth visit — LillyDirect lists independent telehealth at $29 per visit.
Ranked by lowest published entry price. Read the "watch out for" note on each — in this category the entry price is almost never the price you keep paying.
Best With Insurance
Brand-name GLP-1s through an insurance-friendly primary care platform.
Watch out for: If you have no coverage for weight-loss drugs, PlushCare is likely to be one of the more expensive routes, because you pay both the membership and the full cash price of a brand-name medication.
Top Rated 2026
Primary care, pharmacy and delivery under one roof, with insurance billing.
Watch out for: If you specifically want tirzepatide, this is not the platform — the published lineup is semaglutide and orforglipron.
Retail Scale
A retail platform stitching together virtual care, pharmacy and nutrition.
Watch out for: This is a marketplace, not a program, so you are really evaluating Curai, Wheel or Twin Health rather than Walmart.
Provider-Set Pricing
A prescriber marketplace where individual clinicians set their own fees.
Watch out for: The absence of structure is the whole trade-off.
FDA-Approved Only
A flat care subscription bolted onto GoodRx's negotiated brand-name pricing.
Watch out for: The introductory-versus-standard pricing gap is the thing to watch — at $119 a month the subscription is among the more expensive in this category, and that changes the total-cost calculation substantially.
Lowest Visit Fee
A general telehealth clinic with low visit fees and free home delivery.
Watch out for: The inconsistent published medication pricing is a genuine problem for comparison — a $60 a month spread between two of the company's own pages is significant.
After comparing all 28, the meaningful differences come down to six things — not the marketing.
Several compounded providers reserve their best rates for 12-month prepayment. Given that the FDA has ended shortage-related compounding allowances and proposed excluding semaglutide, tirzepatide and liraglutide from the 503B bulks list, prepaying a year of compounded medication is a bet on continued availability. Month-to-month costs more per month but carries far less exposure.
It depends on whether you want brand-name or compounded medication. For FDA-approved medication, Foundayo through LillyDirect or GoodRx starts at $149 a month, and Wegovy tablets through NovoCare Pharmacy start at $149 a month. For compounded, Curex publishes an all-in $149 a month with no membership fee, and LumiMeds and Fridays go lower on long prepaid plans. Teladoc is free for eligible members whose employer or health plan covers it.
The situation has narrowed considerably. The FDA resolved the tirzepatide shortage in December 2024 and the semaglutide shortage in February 2025, which ended the shortage-based enforcement discretion that allowed large-scale compounding. The FDA has since proposed excluding semaglutide, tirzepatide and liraglutide from the 503B bulks list, finding no clinical need for outsourcing facilities to compound them. Compounded GLP-1s remain available from some providers, but they are not FDA-approved and continued availability is not guaranteed.
PlushCare, Amazon One Medical, Klarity Health, Nurx and Teladoc Health all work with insurance in some form. Compounded-only providers such as Curex, TrimRx, Willow, LumiMeds and Fridays never can, because compounded drugs are not FDA-approved and therefore not covered.
A membership or platform fee pays for clinical access — the provider, messaging, dose adjustments. The medication cost is the drug itself. Split-fee providers charge both, so a "$49 membership" plus "$299 medication" is really $348 a month. All-in providers such as Curex and TrimRx bundle everything into one number. Always add both before comparing.
For compounded medication, we would be cautious. The lowest advertised rates almost always require 12-month prepayment, and the regulatory basis for compounded GLP-1s has narrowed substantially. For FDA-approved medication bought manufacturer-direct there is no prepayment involved at all — you buy per fill.
From July 1, 2026 through December 31, 2027, the Medicare GLP-1 Bridge program covers Foundayo tablets, Wegovy in injection and tablet form, and the Zepbound KwikPen at $50 a month for eligible beneficiaries. That is cheaper than any cash-pay provider on this page. Note that Walgreens' virtual weight management service does not currently support Medicare patients.
FDA-approved medication ranked by real cost
With the regulatory caveats spelled out
All-in pricing, no platform charge
What every route actually costs in 2026
The differences that matter clinically and legally
$50/month coverage from July 1, 2026
Claims on this page trace to the following sources, checked on August 30, 2026.
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This article is for informational purposes only and is not medical advice, a diagnosis, or a treatment recommendation. GLP-1 medications are prescription drugs with serious potential side effects and are not appropriate for everyone. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. Individual results vary. This page contains affiliate links, and we may earn compensation if you use them.
Date reviewed: August 30, 2026