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Trimi Review 2026

Flat $99 compounded semaglutide that never changes as your dose goes up

Also searched as: Trimi Health, trytrimi

4.2/5
Our editorial score
Starting at

$99/mo

Medication

Compounded

Insurance

Cash-pay

Reviewed

August 30, 2026

Trimi Overview

Compounded (not FDA-approved)

Trimi publishes compounded semaglutide at $99 a month and compounded tirzepatide at $125 a month on annual plans, and — unusually — holds that price flat at every dose. Your cost does not change as your prescription is titrated up.

That combination is rare. Most providers advertise a low entry rate that applies only to the starting dose and climbs steeply; others charge flat but at a much higher level. Trimi is one of the few offering both a low headline number and no dose escalation.

Trimi also names its pharmacy category publicly, stating that medication is prepared per individual prescription by 503A sterile compounding pharmacies. That is more disclosure than most compounded platforms provide, though the specific pharmacies are still not named.

Medications Offered

  • Compounded semaglutide — $99/mo on the annual plan, flat at every dose
  • Compounded tirzepatide — $125/mo on the annual plan, flat at every dose

Brand-name or compounded?

Trimi dispenses compounded semaglutide and tirzepatide prepared per individual prescription by 503A sterile compounding pharmacies. Compounded drugs are not FDA-approved and the FDA does not evaluate them for safety, effectiveness or quality.

How the Program Works

Consultation process

Online intake reviewed by a US-licensed prescribing clinician, included in the monthly price.

Eligibility

Adults meeting standard GLP-1 criteria as assessed by the reviewing clinician.

Provider involvement

US-licensed prescribing clinicians handle prescribing and dose adjustment, covered by the all-inclusive price.

Lab requirements

Not publicly listed as a standard requirement. Confirm directly with Trimi.

Pharmacy fulfillment

503A sterile compounding pharmacies preparing medication per individual prescription. Trimi discloses the pharmacy category but not the specific partners.

Shipping and frequency

Included in the monthly price. Injectable compounded GLP-1s require refrigerated cold-chain handling.

Support services

Clinician access included. Trimi publishes an extensive public education library, including a 50-question GLP-1 FAQ and detailed competitor pricing comparisons.

Fees, Cancellation and Coverage

Membership fees

None. Trimi states there are no membership charges — the monthly price is all-inclusive.

Medication fees

Included in the monthly price, which covers medication, the US-licensed prescribing clinician and shipping.

Cancellation policy

The lowest rates are on annual billing, which is a commitment. Confirm the specific cancellation terms for your plan length before purchase.

Refund policy

No published blanket refund policy. Compounded medication cannot be returned once dispensed.

Insurance

Not accepted. Compounded GLP-1s are not FDA-approved and are not covered by insurance.

HSA / FSA

Reimbursement for compounded medication is uncertain. Confirm with your plan administrator before purchase.

Pricing in this review reflects what Trimi and named third-party sources published as of August 30, 2026. Telehealth pricing changes frequently — confirm the current figure at checkout before you buy.

Pros and Cons

Pros

  • +$99/mo for compounded semaglutide is among the lowest published all-in prices
  • +Price stays flat at every dose — no escalation as you titrate
  • +No membership fee stacked on top of the medication cost
  • +Discloses that medication comes from 503A sterile compounding pharmacies
  • +Tirzepatide at $125/mo is well below most competitors
  • +Extensive public education library and transparent competitor comparisons

Cons

  • The $99 and $125 rates require annual billing
  • Compounded medications are not FDA-approved
  • Specific compounding pharmacy partners are not named
  • Annual prepayment is risky given the narrowing regulatory position on compounded GLP-1s
  • No insurance coverage possible
  • Lab requirements are not clearly published

Who It May Be Best For

Best for

Cost-sensitive patients who expect to titrate to a higher maintenance dose and want the price to stay put, and who are comfortable committing to an annual plan.

Limitations to weigh

The annual commitment is the catch, and it matters more than usual here. The FDA has ended the shortage-based compounding allowances and proposed excluding semaglutide and tirzepatide from the 503B bulks list, so a twelve-month commitment to a compounded program carries real availability risk.

Frequently Asked Questions

How much does Trimi cost?

Trimi publishes compounded semaglutide at $99 a month and compounded tirzepatide at $125 a month on annual plans, working out to $1,188 a year all-inclusive for semaglutide. The price covers medication, the US-licensed prescribing clinician and shipping, with no membership fee.

Does Trimi's price change as my dose increases?

No. Trimi holds the price flat at every dose, so your cost does not change as your prescription is titrated up. That is unusual — most competitors advertise a starting-dose rate that climbs steeply.

Are Trimi medications FDA-approved?

No. Trimi dispenses compounded semaglutide and tirzepatide prepared per individual prescription by 503A sterile compounding pharmacies. Compounded drugs are not FDA-approved and the FDA does not evaluate them for safety, effectiveness or quality.

Is Trimi the same company as TrimRx?

No, they are separate companies with similar names and very different pricing. TrimRx charges $199 a month for compounded semaglutide and $299 to $349 for tirzepatide; Trimi runs $99 and $125 respectively on annual plans.

Does Trimi charge a membership fee?

No. Trimi states there are no membership charges and no hidden fees — the monthly figure is all-inclusive, covering medication, clinician and shipping.

What pharmacy does Trimi use?

Trimi states its medication is prepared per individual prescription by 503A sterile compounding pharmacies. It discloses the pharmacy category but does not publicly name the specific partners, which is worth asking about directly.

Sources

Every pricing and policy claim on this page traces back to one of these sources, checked on August 30, 2026.

Pricing

STARTING PRICE
Compounded semaglutide (annual)$99/mo

$1,188/year all-inclusive; flat at every dose

Compounded tirzepatide (annual)$125/mo

Flat at every dose

Membership fee$0

Trimi states no membership charges and no hidden fees

Check Current PricingRead the GLP-1 Cost Guide

Verified August 30, 2026. Prices change often — confirm before purchase.

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Medical disclaimer

This review is for informational purposes only and is not medical advice, a diagnosis, or a treatment recommendation. GLP-1 medications are prescription drugs with serious potential side effects and are not appropriate for everyone. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. Compounded medications are not FDA-approved. The FDA does not evaluate compounded products for safety, effectiveness, or quality. Individual results vary. This page contains affiliate links, and we may earn compensation if you use them.

Date reviewed: August 30, 2026